Basic Information
ID: ALA4623541
Type: Binding
Description: Inhibition of calf thymus Top1 assessed as reduction in Top1-supercoiled pBR322 DNA covalent cleavage formation at 25 to 50 uM measured after 30 mins by electrophoretic mobility shift assay
Organism: Bos taurus
Activity Charts
Bioactivity
Activity Types for Assay ALA4623541
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.70 | 7.30 | 7.30 |
| 388.55 | 5.06 | 5.06 |
| 648.88 | 8.18 | 8.18 |