Basic Information
ID: ALA4623754
Type: Functional
Description: Positive allosteric modulation of recombinant human muscarinic acetylcholine receptor M3 expressed in CHOK1 cells assessed as increase in carbachol-induced intracellular calcium flux at 10 uM preincubated for 5 mins followed by carbachol addition by Fluo4-AM dye based FLIPR assay relative to carbachol
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA4623754
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 556.05 | 6.42 | 6.42 |
| 630.73 | 5.02 | 5.02 |
| 620.03 | 4.85 | 4.85 |
| 549.58 | 5.20 | 5.20 |
| 691.60 | 5.56 | 5.56 |
| 677.58 | 5.17 | 5.17 |
| 707.60 | 4.79 | 4.79 |
| 617.69 | 4.97 | 4.97 |
| 705.63 | 5.95 | 5.95 |
| 705.63 | 5.80 | 5.80 |
| 682.00 | 5.81 | 5.81 |
| 682.00 | 5.81 | 5.81 |
| 619.04 | 5.46 | 5.46 |
| 723.65 | 5.29 | 5.29 |
| 614.09 | 6.18 | 6.18 |
| 691.60 | 5.56 | 5.56 |
| 616.71 | 5.00 | 5.00 |
| 547.11 | 4.85 | 4.85 |
| 677.58 | 5.17 | 5.17 |
| 637.03 | 5.60 | 5.60 |