Assay Report Card

Basic Information

ID: ALA4623755

Type: Functional

Description: Positive allosteric modulation of recombinant rat muscarinic acetylcholine receptor M1 expressed in CHOK1 cells assessed as increase in carbachol-induced intracellular calcium flux at 10 uM preincubated for 5 mins followed by carbachol addition by Fluo4-AM dye based FLIPR assay relative to carbachol

Organism: Rattus norvegicus

Cell type: CHO-K1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
691.605.565.56