Assay Report Card

Basic Information

ID: ALA4623756

Type: Functional

Description: Positive allosteric modulation of recombinant human muscarinic acetylcholine receptor M2 expressed in CHOK1 cells coexpressing G-alpha16 assessed as increase in carbachol-induced intracellular calcium flux at 10 uM preincubated for 5 mins followed by carbachol addition by Fluo4-AM based FLIPR assay relative to carbachol

Organism: Homo sapiens

Cell type: CHO-K1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
691.605.565.56