Basic Information
ID: ALA4623829
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes assessed as enzyme residual activity at 10 uM using midazolam as substrate measured after 30 mins by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4623829
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 441.49 | 3.07 | 3.07 |
| 440.50 | 3.67 | 3.67 |
| 454.52 | 4.06 | 4.06 |
| 449.48 | 3.39 | 3.39 |
| 455.51 | 3.37 | 3.37 |
| 455.51 | 3.46 | 3.46 |
| 435.46 | 3.00 | 3.00 |