Basic Information
ID: ALA4624029
Type: Functional
Description: Antagonist activity at human recombinant OX2R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intracellular Ca2+ release preincubated for 30 mins followed by orexin-A stimulation by Fluo-4AM dye based fluorescence analysis
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA4624029
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.46 | 3.14 | 3.14 |
| 405.44 | 2.83 | 2.83 |
| 433.45 | 2.55 | 2.55 |
| 445.50 | 3.67 | 3.67 |
| 449.52 | 3.19 | 3.19 |
| 433.45 | 2.47 | 2.47 |
| 449.52 | 3.19 | 3.19 |
| 448.46 | 2.26 | 2.26 |
| 462.46 | 3.57 | 3.57 |
| 431.48 | 3.28 | 3.28 |
| 447.47 | 2.73 | 2.73 |
| 448.46 | 2.26 | 2.26 |
| 446.49 | 3.47 | 3.47 |
| 447.47 | 2.86 | 2.86 |
| 445.50 | 3.67 | 3.67 |
| 451.44 | 2.69 | 2.69 |
| 447.47 | 2.86 | 2.86 |
| 449.45 | 2.59 | 2.59 |
| 433.45 | 2.47 | 2.47 |
| 458.50 | 3.74 | 3.74 |
| 447.47 | 2.51 | 2.51 |
| 447.47 | 2.86 | 2.86 |
| 431.48 | 3.28 | 3.28 |
| 464.46 | 1.35 | 1.35 |
| 447.47 | 2.86 | 2.86 |
| 433.45 | 2.47 | 2.47 |