Basic Information
ID: ALA4624195
Type: Binding
Description: Agonist activity at human TAS2R46 expressed in human BEAS2B cells assessed as antiinflammatory activity by measuring reduction in PMA-induced IL-1beta gene expression at 1 uM incubated for 18 hrs in presence of 1 uM TAS2R46 antagonist 3HDC by qRT-PCR analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4624195
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 600.80 | 6.21 | 6.21 |
| 536.67 | 5.20 | 5.20 |
| 510.67 | 4.60 | 4.60 |
| 496.64 | 3.80 | 3.80 |