Agonist activity at human TAS2R46 expressed in human BEAS2B cells assessed as antiinflammatory activity by measuring reduction in PMA-induced IL-1beta...

Basic Information

ID: ALA4624196

Type: Binding

Description: Agonist activity at human TAS2R46 expressed in human BEAS2B cells assessed as antiinflammatory activity by measuring reduction in PMA-induced IL-1beta gene expression at 10 uM incubated for 18 hrs in presence of 1 uM TAS2R46 antagonist 3HDC by qRT-PCR analysis

Format: BAO_0000219

Organism: Homo sapiens

Target:  Taste receptor type 2 member 46(ALA4523253)

Document:  ALA4622880

Agonist activity at human TAS2R46 expressed in human BEAS2B cells assessed as antiinflammatory activity by measuring reduction in PMA-induced IL-1beta gene expression at 10 uM incubated for 18 hrs in presence of 1 uM TAS2R46 antagonist 3HDC by qRT-PCR analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
496.643.803.80