Assay Report Card

Basic Information

ID: ALA4625180

Type: Binding

Description: Binding affinity to murine DNMT3A catalytic domain assessed as enzyme-DNA complex formation at 30 uM using 30-mer duplex DNA (22 AT bp) as substrate preincubated for 30 mins followed by enzyme addition by fluorescence polarization assay (Rvb = 0.4 +/- 0.1 uM)

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
336.444.204.20