Assay Report Card

Basic Information

ID: ALA4625538

Type: Binding

Description: Inhibition of Escherichia coli BL21(DE3) ileRS overexpressed in Escherichia coli Rosetta2(DE3) assessed as reduction in tRNA aminoacylation at 1 uM preincubated with enzyme and substrate for 10 mins prior to ATP addition using 14C-labeled isoleucine and tRNA as substrate by liquid scintillation counting method

Organism: Escherichia coli BL21(DE3)

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
525.630.210.21
512.59-0.78-0.78
511.60-0.18-0.18
527.60-0.80-0.80