Assay Report Card

Basic Information

ID: ALA4625541

Type: Binding

Description: Inhibition of Escherichia coli BL21(DE3) TyrRS overexpressed in Escherichia coli Rosetta2(DE3) assessed as reduction in tRNA aminoacylation at 5 uM preincubated with enzyme and substrate for 10 mins prior to ATP addition using 14C-labeled tyrosine and tRNA as substrate by liquid scintillation counting method

Organism: Escherichia coli BL21(DE3)

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
562.61-0.88-0.88
561.62-0.27-0.27
577.62-0.90-0.90