Basic Information
ID: ALA4625601
Type: Binding
Description: Potency index, ratio of MB872 IC50 to test compound IC50 for recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor by fluorimetric analysis
Organism: Mycobacterium tuberculosis
Activity Charts
Bioactivity
Activity Types for Assay ALA4625601
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 258.27 | 2.97 | 2.97 |
| 272.30 | 3.06 | 3.06 |
| 273.24 | 2.87 | 2.87 |
| 227.26 | 3.00 | 3.00 |
| 244.25 | 2.67 | 2.67 |
| 287.27 | 2.96 | 2.96 |