Basic Information
ID: ALA4625932
Type: Binding
Description: Inhibition of His-tagged BLM (642 to 1296 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in DNA unwinding activity at <10 uM using 5'-biotin-labeled forked DNA as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by electrophoretic mobility shift assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4625932
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 449.57 | 4.30 | 4.30 |
| 436.53 | 4.24 | 4.24 |
| 431.60 | 6.74 | 6.74 |
| 495.64 | 4.57 | 4.57 |
| 419.54 | 6.06 | 6.06 |
| 438.50 | 3.64 | 3.64 |
| 412.53 | 4.30 | 4.30 |
| 436.58 | 5.50 | 5.50 |
| 450.60 | 5.14 | 5.14 |
| 421.52 | 5.05 | 5.05 |
| 464.63 | 5.22 | 5.22 |
| 399.58 | 6.21 | 6.21 |
| 406.51 | 4.23 | 4.23 |
| 451.59 | 4.09 | 4.09 |
| 464.63 | 5.32 | 5.32 |
| 441.66 | 7.06 | 7.06 |
| 462.61 | 5.75 | 5.75 |
| 413.61 | 6.43 | 6.43 |
| 420.53 | 4.62 | 4.62 |
| 379.48 | 5.28 | 5.28 |
| 438.50 | 3.64 | 3.64 |
| 434.52 | 4.15 | 4.15 |
| 441.66 | 7.16 | 7.16 |
| 466.60 | 4.85 | 4.85 |