Assay Report Card

Basic Information

ID: ALA4626083

Type: Binding

Description: Activation of N-terminal his-tagged human SIRT6 expressed in Escherichia coli M15 [pREP4] assessed as increase in peptide demyristoylation incubated for 120 mins using Ac-EALPKK(Myr)-AMC substrate by FDL assay relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
284.313.523.52
394.483.133.13
469.954.034.03
626.315.595.59
447.326.886.88
392.465.895.89
428.495.575.57
496.877.587.58
486.886.846.84
412.495.795.79
430.816.736.73
412.495.165.16
476.536.966.96
432.406.926.92
454.537.177.17
426.526.106.10
416.454.994.99
486.886.846.84
406.496.836.83
455.526.566.56
382.396.046.04
520.437.217.21
392.466.526.52
432.916.136.13
470.836.566.56
453.336.486.48
474.566.446.44
466.857.577.57
466.857.577.57
396.425.725.72
467.356.166.16
433.297.217.21
412.886.866.86
434.506.326.32
500.407.947.94
484.866.606.60
453.336.486.48
456.856.836.83