Basic Information
ID: ALA4626084
Type: Binding
Description: Activation of N-terminal his-tagged human SIRT6 expressed in Escherichia coli M15 [pREP4] assessed as increase in peptide demyristoylation at 20 uM incubated for 120 mins using Ac-EALPKK(Myr)-AMC substrate by FDL assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4626084
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 463.52 | 3.82 | 3.82 |
| 432.85 | 6.89 | 6.89 |
| 477.54 | 4.13 | 4.13 |
| 376.46 | 4.59 | 4.59 |
| 444.49 | 5.19 | 5.19 |
| 402.43 | 5.31 | 5.31 |
| 447.32 | 6.88 | 6.88 |
| 463.88 | 5.73 | 5.73 |
| 392.46 | 5.89 | 5.89 |
| 428.49 | 5.57 | 5.57 |
| 512.65 | 7.47 | 7.47 |
| 414.46 | 7.05 | 7.05 |
| 418.88 | 5.82 | 5.82 |
| 402.43 | 5.31 | 5.31 |
| 496.87 | 7.58 | 7.58 |
| 428.49 | 5.57 | 5.57 |
| 452.43 | 6.19 | 6.19 |
| 486.88 | 6.84 | 6.84 |
| 402.43 | 5.31 | 5.31 |
| 436.87 | 5.96 | 5.96 |
| 408.46 | 6.30 | 6.30 |
| 412.49 | 5.79 | 5.79 |
| 430.81 | 6.73 | 6.73 |
| 412.49 | 5.16 | 5.16 |
| 440.54 | 6.60 | 6.60 |
| 476.53 | 6.96 | 6.96 |
| 432.40 | 6.92 | 6.92 |
| 454.53 | 7.17 | 7.17 |
| 420.42 | 5.45 | 5.45 |
| 426.52 | 6.10 | 6.10 |
| 416.45 | 4.99 | 4.99 |
| 486.88 | 6.84 | 6.84 |
| 414.46 | 5.18 | 5.18 |
| 406.49 | 6.83 | 6.83 |
| 416.79 | 6.42 | 6.42 |
| 519.60 | 5.18 | 5.18 |
| 455.52 | 6.56 | 6.56 |
| 477.54 | 5.11 | 5.11 |
| 382.39 | 6.04 | 6.04 |
| 502.59 | 5.90 | 5.90 |
| 520.43 | 7.21 | 7.21 |
| 434.50 | 6.32 | 6.32 |
| 350.42 | 4.06 | 4.06 |
| 392.46 | 6.52 | 6.52 |
| 432.91 | 6.13 | 6.13 |
| 470.83 | 6.56 | 6.56 |
| 446.88 | 7.20 | 7.20 |
| 474.84 | 6.97 | 6.97 |
| 453.33 | 6.48 | 6.48 |
| 474.56 | 6.44 | 6.44 |
| 466.85 | 7.57 | 7.57 |
| 466.85 | 7.57 | 7.57 |
| 396.42 | 5.72 | 5.72 |
| 463.33 | 5.93 | 5.93 |
| 447.42 | 5.22 | 5.22 |
| 476.55 | 5.64 | 5.64 |
| 467.35 | 6.16 | 6.16 |
| 418.88 | 5.82 | 5.82 |
| 398.46 | 5.48 | 5.48 |
| 432.87 | 7.21 | 7.21 |
| 433.29 | 7.21 | 7.21 |
| 398.46 | 4.85 | 4.85 |
| 443.53 | 5.72 | 5.72 |
| 502.00 | 6.95 | 6.95 |
| 459.46 | 5.09 | 5.09 |
| 412.88 | 6.86 | 6.86 |
| 427.81 | 6.22 | 6.22 |
| 418.85 | 6.82 | 6.82 |
| 391.47 | 3.31 | 3.31 |
| 418.88 | 5.82 | 5.82 |
| 454.88 | 7.44 | 7.44 |
| 440.85 | 7.13 | 7.13 |
| 440.54 | 6.47 | 6.47 |
| 432.91 | 6.13 | 6.13 |
| 455.56 | 6.02 | 6.02 |
| 434.50 | 6.32 | 6.32 |
| 456.50 | 5.35 | 5.35 |
| 500.40 | 7.94 | 7.94 |
| 459.46 | 5.09 | 5.09 |
| 474.56 | 4.63 | 4.63 |
| 484.86 | 6.60 | 6.60 |
| 433.29 | 7.21 | 7.21 |
| 538.63 | 6.99 | 6.99 |
| 458.56 | 4.73 | 4.73 |
| 456.50 | 7.69 | 7.69 |
| 447.42 | 5.22 | 5.22 |
| 453.33 | 6.48 | 6.48 |
| 456.85 | 6.83 | 6.83 |