Basic Information
ID: ALA4626182
Type: ADME
Description: Inhibition of recombinant human ALK5 expressed in HEK293 cells transfected with CAGA-luciferase and Renilla luciferase reporter after 24 hrs by dual luciferase reporter assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: TGF-beta receptor type I(ALA4439)
Document: ALA4622974
Inhibition of recombinant human ALK5 expressed in HEK293 cells transfected with CAGA-luciferase and Renilla luciferase reporter after 24 hrs by dual luciferase reporter assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4626182
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.53 | 4.16 | 4.16 |
| 423.49 | 3.99 | 3.99 |
| 432.56 | 5.56 | 5.56 |
| 435.52 | 3.86 | 3.86 |
| 447.58 | 4.94 | 4.94 |
| 418.54 | 5.22 | 5.22 |
| 420.51 | 3.43 | 3.43 |
| 473.50 | 4.87 | 4.87 |
| 407.49 | 4.29 | 4.29 |
| 389.50 | 4.15 | 4.15 |
| 430.51 | 3.72 | 3.72 |
| 497.62 | 3.83 | 3.83 |
| 447.58 | 4.50 | 4.50 |
| 433.55 | 4.55 | 4.55 |
| 490.60 | 4.55 | 4.55 |
| 416.52 | 5.13 | 5.13 |
| 433.55 | 4.41 | 4.41 |
| 439.94 | 4.50 | 4.50 |
| 420.51 | 4.59 | 4.59 |
| 433.55 | 4.50 | 4.50 |
| 461.61 | 5.28 | 5.28 |
| 418.47 | 3.85 | 3.85 |
| 445.56 | 4.73 | 4.73 |
| 430.55 | 5.47 | 5.47 |
| 448.56 | 5.22 | 5.22 |
| 465.57 | 4.84 | 4.84 |
| 434.54 | 4.88 | 4.88 |
| 461.56 | 4.42 | 4.42 |
| 468.58 | 3.98 | 3.98 |