Basic Information
ID: ALA4626294
Type: ADME
Description: Inhibition of SHP2 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis spectrophotometric method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4626294
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 165.15 | 0.71 | 0.71 |
| 382.37 | 1.67 | 1.67 |
| 335.28 | 3.90 | 3.90 |
| 368.35 | 1.58 | 1.58 |
| 269.30 | 2.49 | 2.49 |
| 318.33 | 1.59 | 1.59 |
| 309.28 | 1.81 | 1.81 |
| 315.33 | 3.26 | 3.26 |
| 265.27 | 2.11 | 2.11 |
| 371.39 | 3.69 | 3.69 |
| 368.35 | 1.58 | 1.58 |
| 339.30 | 1.60 | 1.60 |
| 216.20 | 1.26 | 1.26 |
| 412.16 | 3.89 | 3.89 |
| 333.27 | 3.13 | 3.13 |
| 351.26 | 3.27 | 3.27 |
| 241.25 | 2.38 | 2.38 |
| 382.37 | 1.67 | 1.67 |
| 358.28 | 3.00 | 3.00 |
| 267.28 | 2.88 | 2.88 |
| 344.35 | 0.76 | 0.76 |
| 241.25 | 2.38 | 2.38 |
| 360.16 | 2.58 | 2.58 |
| 321.38 | 3.41 | 3.41 |
| 380.40 | 3.46 | 3.46 |
| 339.30 | 1.60 | 1.60 |
| 367.71 | 3.78 | 3.78 |
| 333.27 | 3.13 | 3.13 |
| 337.30 | 3.51 | 3.51 |
| 265.27 | 2.11 | 2.11 |
| 281.27 | 1.82 | 1.82 |
| 401.26 | 4.15 | 4.15 |
| 189.17 | 0.69 | 0.69 |
| 401.26 | 4.15 | 4.15 |
| 349.26 | 3.01 | 3.01 |
| 290.28 | 1.98 | 1.98 |