Basic Information
ID: ALA4626980
Type: Binding
Description: Displacement of Alexa Fluor 647 labelled I-BET762 from N-terminal His6-tagged human BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant expressed in Escherichia coli after 1 hr by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4626980
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 415.45 | 4.16 | 4.16 |
| 486.58 | 4.15 | 4.15 |
| 429.48 | 4.17 | 4.17 |
| 473.53 | 3.93 | 3.93 |
| 484.56 | 3.91 | 3.91 |
| 442.52 | 5.62 | 5.62 |
| 486.58 | 4.10 | 4.10 |
| 511.63 | 5.60 | 5.60 |
| 457.49 | 3.79 | 3.79 |
| 443.46 | 3.86 | 3.86 |
| 484.56 | 4.03 | 4.03 |
| 484.56 | 4.03 | 4.03 |
| 458.52 | 3.50 | 3.50 |
| 498.59 | 4.15 | 4.15 |
| 472.55 | 3.89 | 3.89 |
| 498.59 | 4.15 | 4.15 |
| 484.56 | 3.91 | 3.91 |
| 500.60 | 4.49 | 4.49 |
| 512.61 | 4.54 | 4.54 |
| 473.49 | 3.63 | 3.63 |
| 514.59 | 4.07 | 4.07 |