Basic Information
ID: ALA4626982
Type: Binding
Description: Displacement of Alexa Fluor 647 labelled I-BET762 from N-terminal His6-tagged human BRD2 BD1 (1 to 473 residues)/BD2 Y386A mutant expressed in Escherichia coli after 1 hr by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4626982
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 415.45 | 4.16 | 4.16 |
| 442.52 | 5.62 | 5.62 |
| 511.63 | 5.60 | 5.60 |