Assay Report Card

Basic Information

ID: ALA4627020

Type: Binding

Description: Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled ribonucleotide monophosphates incorporation into RNA using cIRES template measured after 2 hrs by microscintillation counting method

Organism: Hepatitis C virus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
539.20-0.97-0.97
537.21-1.95-1.95
539.20-0.97-0.97
565.19-2.04-2.04
541.190.010.01
555.20-1.65-1.65
557.650.280.28
557.19-0.67-0.67
555.65-0.70-0.70
567.18-1.06-1.06