Basic Information
ID: ALA4627634
Type: Functional
Description: Induction of DNA damage in human SU8686 cells assessed as increase in gammaH2AX phosphorylation at ser193 at cytotoxic IC50 in presence of 5 uM cisplatin by fluorometry method
Organism: Homo sapiens
Cell type: SU.86.86
Activity Charts
Bioactivity
Activity Types for Assay ALA4627634
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 501.79 | 6.23 | 6.23 |
| 564.77 | 6.56 | 6.56 |
| 322.36 | 4.38 | 4.38 |
| 580.77 | 5.96 | 5.96 |
| 336.30 | -1.08 | -1.08 |
| 312.45 | 4.81 | 4.81 |
| 386.58 | 6.55 | 6.55 |
| 358.48 | 4.67 | 4.67 |
| 1126.40 | ||
| 272.26 | 3.04 | 3.04 |
| 447.62 | 5.86 | 5.86 |
| 638.58 | 1.85 | 1.85 |
| 1477.90 | ||
| 381.47 | 3.40 | 3.40 |
| 352.34 | 1.57 | 1.57 |
| 438.64 | 5.58 | 5.58 |
| 418.44 | 3.94 | 3.94 |