Basic Information
ID: ALA4627635
Type: Functional
Description: Induction of DNA damage in human SU8686 cells assessed as increase in gammaH2AX phosphorylation at ser193 at cytotoxic IC50 in presence of 0.3 uM doxorubicin by fluorometry method
Organism: Homo sapiens
Cell type: SU.86.86
Activity Charts
Bioactivity
Activity Types for Assay ALA4627635
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 142.11 | -0.16 | -0.16 |
| 270.24 | 1.37 | 1.37 |
| 358.39 | 2.69 | 2.69 |
| 818.11 | 2.84 | 2.84 |
| 501.79 | 6.23 | 6.23 |
| 564.77 | 6.56 | 6.56 |
| 256.39 | 5.34 | 5.34 |
| 314.47 | 5.44 | 5.44 |
| 322.36 | 4.38 | 4.38 |
| 218.34 | 4.55 | 4.55 |
| 389.46 | 2.38 | 2.38 |
| 580.77 | 5.96 | 5.96 |
| 566.79 | 6.39 | 6.39 |
| 336.30 | -1.08 | -1.08 |
| 284.27 | 2.19 | 2.19 |
| 312.45 | 4.81 | 4.81 |
| 324.38 | 4.21 | 4.21 |
| 386.58 | 6.55 | 6.55 |
| 358.48 | 4.67 | 4.67 |
| 338.98 | 1.54 | 1.54 |
| 538.46 | 3.75 | 3.75 |
| 272.26 | 2.67 | 2.67 |
| 436.10 | 1.61 | 1.61 |
| 115.18 | 1.05 | 1.05 |
| 401.20 | 3.44 | 3.44 |
| 1126.40 | ||
| 237.26 | 2.90 | 2.90 |
| 272.26 | 3.04 | 3.04 |
| 296.95 | 2.72 | 2.72 |
| 1114.02 | ||
| 281.94 | 1.57 | 1.57 |
| 208.21 | 1.76 | 1.76 |
| 446.50 | 4.72 | 4.72 |
| 789.93 | 2.51 | 2.51 |
| 667.88 | 3.93 | 3.93 |
| 638.58 | 1.85 | 1.85 |
| 419.52 | 2.18 | 2.18 |
| 538.73 | 4.78 | 4.78 |
| 163.18 | 1.47 | 1.47 |