Basic Information
ID: ALA4627647
Type: Functional
Description: Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate at 30 uM to 1 nM incubated for 1 hr followed by IP1-d2 addition by HTRF assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Probable G-protein coupled receptor 142(ALA2069161)
Document: ALA4627259
Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate at 30 uM to 1 nM incubated for 1 hr followed by IP1-d2 addition by HTRF assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4627647
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 476.46 | 3.21 | 3.21 |
| 448.45 | 3.52 | 3.52 |
| 447.46 | 4.00 | 4.00 |
| 464.45 | 3.40 | 3.40 |
| 491.56 | 4.04 | 4.04 |
| 414.90 | 3.16 | 3.16 |
| 438.91 | 4.38 | 4.38 |
| 488.51 | 4.71 | 4.71 |
| 446.48 | 4.33 | 4.33 |
| 506.45 | 4.92 | 4.92 |
| 521.58 | 3.81 | 3.81 |
| 474.49 | 4.02 | 4.02 |
| 436.90 | 3.77 | 3.77 |
| 462.52 | 4.89 | 4.89 |
| 496.48 | 5.06 | 5.06 |
| 432.45 | 4.32 | 4.32 |
| 460.46 | 3.63 | 3.63 |
| 438.45 | 3.90 | 3.90 |
| 488.51 | 4.40 | 4.40 |
| 472.46 | 4.74 | 4.74 |
| 422.45 | 4.02 | 4.02 |
| 412.93 | 3.97 | 3.97 |
| 446.48 | 4.33 | 4.33 |
| 450.51 | 5.06 | 5.06 |
| 490.45 | 5.04 | 5.04 |