Assay Report Card

Basic Information

ID: ALA4627766

Type: Binding

Description: Agonist activity at TLR8 in human PBMC assessed as induction of myeloid dendritic cell maturation by measuring HLA-DR level at 0.1 uM after 6 hrs by flow cytometry

Organism: Homo sapiens

Cell type: PBMC

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
356.860.880.88
412.972.442.44
400.910.580.58
370.891.271.27
413.950.940.94
370.891.271.27
414.940.970.97
426.992.832.83
355.870.910.91
372.86-0.15-0.15
399.930.550.55
358.83-0.27-0.27