Basic Information
ID: ALA4627976
Type: Binding
Description: Inhibition of NS5B polymerase in HCV genotype 1a H77 infected in human HuH7 replicon cells assessed as inhibition of viral replication after 3 days by luciferase reporter gene assay
Organism: Hepatitis C virus subtype 1a
Strain: H77
Cell type: Huh-7
Activity Charts
Bioactivity
Activity Types for Assay ALA4627976
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 529.46 | 1.66 | 1.66 |
| 624.81 | 2.51 | 2.51 |
| 624.81 | 2.65 | 2.65 |
| 759.98 | 3.95 | 3.95 |
| 610.78 | 2.26 | 2.26 |
| 610.78 | 2.26 | 2.26 |
| 596.76 | 1.87 | 1.87 |
| 610.78 | 2.26 | 2.26 |
| 709.92 | 2.79 | 2.79 |
| 626.78 | 1.50 | 1.50 |
| 660.84 | 3.41 | 3.41 |
| 640.81 | 1.88 | 1.88 |
| 596.76 | 1.87 | 1.87 |
| 654.84 | 2.13 | 2.13 |
| 640.81 | 2.27 | 2.27 |