Basic Information
ID: ALA4627981
Type: ADME
Description: Prodrug conversion in human hepatocytes assessed as nucleotide triphosphate level at 100 uM incubated for 4 hrs followed by compound washout and further incubated in fresh media for 24 hrs
Organism: Homo sapiens
Cell type: Hepatocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA4627981
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 529.46 | 1.66 | 1.66 |
| 624.81 | 2.51 | 2.51 |
| 624.81 | 2.65 | 2.65 |
| 759.98 | 3.95 | 3.95 |
| 610.78 | 2.26 | 2.26 |
| 610.78 | 2.26 | 2.26 |
| 596.76 | 1.87 | 1.87 |
| 610.78 | 2.26 | 2.26 |
| 709.92 | 2.79 | 2.79 |
| 626.78 | 1.50 | 1.50 |
| 660.84 | 3.41 | 3.41 |
| 640.81 | 1.88 | 1.88 |
| 596.76 | 1.87 | 1.87 |
| 654.84 | 2.13 | 2.13 |
| 640.81 | 2.27 | 2.27 |