Basic Information
ID: ALA4628023
Type: ADME
Description: Inhibition of recombinant human N-terminal His-tagged Abl (2 to 1130 residues) expressed in baculovirus expression system using FAM-labelled P2 peptide as substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr in presence of ATP by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4628023
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 529.53 | 6.36 | 6.36 |
| 496.59 | 5.34 | 5.34 |
| 516.65 | 7.28 | 7.28 |
| 572.72 | 5.69 | 5.69 |
| 532.60 | 5.96 | 5.96 |
| 590.71 | 6.00 | 6.00 |
| 389.50 | 3.49 | 3.49 |
| 451.45 | 6.55 | 6.55 |
| 532.65 | 5.83 | 5.83 |
| 563.64 | 5.92 | 5.92 |
| 544.66 | 5.35 | 5.35 |
| 619.70 | 6.52 | 6.52 |
| 530.59 | 6.04 | 6.04 |
| 558.69 | 5.69 | 5.69 |
| 528.54 | 6.96 | 6.96 |
| 567.68 | 4.77 | 4.77 |
| 495.63 | 5.46 | 5.46 |
| 618.72 | 5.92 | 5.92 |
| 577.66 | 6.30 | 6.30 |
| 481.60 | 5.29 | 5.29 |
| 518.62 | 4.60 | 4.60 |