Basic Information
ID: ALA4628056
Type: Binding
Description: Inhibition of PCSK9 D374Y mutant (unknown origin) and LDLR protein-protein interaction in human HepG2 cells assessed as increase in Bodipy FL-labelled LDL uptake preincubated for 16 hrs followed by Bodipy FL-labelled LDL addition and measured after 4 hrs by fluorescence assay
Organism: Homo sapiens
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA4628056
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 532.65 | 5.83 | 5.83 |
| 558.69 | 5.69 | 5.69 |
| 495.63 | 5.46 | 5.46 |