Basic Information
ID: ALA4628081
Type: Binding
Description: Inhibition of NLRP3 inflammasome (unknown origin) activation in LPS-primed bone marrow derived macrophage cells assessed as effect on IL-1beta production in presence of nigericin by ELISA
Format: BAO_0000019
Organism: Homo sapiens
Target: NACHT, LRR and PYD domains-containing protein 3(ALA1741208)
Document: ALA4627283
Inhibition of NLRP3 inflammasome (unknown origin) activation in LPS-primed bone marrow derived macrophage cells assessed as effect on IL-1beta production in presence of nigericin by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4628081
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 423.44 | 4.81 | 4.81 |
| 409.41 | 4.81 | 4.81 |
| 431.40 | 4.12 | 4.12 |
| 507.56 | 4.38 | 4.38 |
| 478.52 | 4.58 | 4.58 |
| 437.46 | 4.85 | 4.85 |
| 468.56 | 3.39 | 3.39 |
| 373.43 | 3.93 | 3.93 |
| 439.44 | 4.68 | 4.68 |
| 475.52 | 4.72 | 4.72 |
| 494.52 | 4.46 | 4.46 |
| 484.52 | 6.36 | 6.36 |
| 447.47 | 4.29 | 4.29 |
| 492.54 | 4.71 | 4.71 |
| 407.37 | 4.64 | 4.64 |
| 505.59 | 4.49 | 4.49 |
| 356.43 | 3.18 | 3.18 |
| 431.54 | 5.45 | 5.45 |
| 461.49 | 4.33 | 4.33 |
| 451.49 | 5.24 | 5.24 |
| 491.56 | 4.50 | 4.50 |