Inhibition of NLRP3 inflammasome (unknown origin) activation in LPS-primed bone marrow derived macrophages assessed as inhibition of IL-1beta secretio...

Basic Information

ID: ALA4628086

Type: Binding

Description: Inhibition of NLRP3 inflammasome (unknown origin) activation in LPS-primed bone marrow derived macrophages assessed as inhibition of IL-1beta secretion at 5 uM in presence of nigericin by ELISA

Format: BAO_0000357

Organism: Homo sapiens

Target:  NACHT, LRR and PYD domains-containing protein 3(ALA1741208)

Document:  ALA4627283

Inhibition of NLRP3 inflammasome (unknown origin) activation in LPS-primed bone marrow derived macrophages assessed as inhibition of IL-1beta secretion at 5 uM in presence of nigericin by ELISA: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
423.444.814.81