Basic Information
ID: ALA4628152
Type: Binding
Description: Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-based assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Smoothened homolog(ALA5971)
Document: ALA4627286
Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4628152
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.31 | 4.71 | 4.71 |
| 512.51 | 4.93 | 4.93 |
| 447.54 | 3.55 | 3.55 |
| 499.51 | 5.96 | 5.96 |
| 524.52 | 5.84 | 5.84 |
| 524.52 | 5.84 | 5.84 |
| 529.53 | 5.97 | 5.97 |
| 475.45 | 3.92 | 3.92 |
| 471.45 | 5.19 | 5.19 |
| 462.51 | 3.45 | 3.45 |
| 485.51 | 4.56 | 4.56 |
| 435.50 | 3.68 | 3.68 |
| 500.50 | 5.36 | 5.36 |
| 543.52 | 5.66 | 5.66 |
| 503.50 | 4.70 | 4.70 |
| 442.52 | 3.41 | 3.41 |
| 529.53 | 5.97 | 5.97 |
| 459.55 | 3.74 | 3.74 |
| 495.61 | 2.94 | 2.94 |
| 575.61 | 7.63 | 7.63 |
| 500.50 | 5.36 | 5.36 |
| 500.50 | 5.36 | 5.36 |