Basic Information
ID: ALA4628173
Type: Functional
Description: Positive allosteric modulation of human TIR2/TIR3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calcium influx by measuring sucrose EC50 at 30 uM measured for 120 secs by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4628173
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 391.47 | 1.49 | 1.49 |
| 377.45 | 1.10 | 1.10 |
| 504.63 | 2.02 | 2.02 |
| 363.42 | 0.59 | 0.59 |
| 377.45 | 1.10 | 1.10 |
| 350.42 | 2.17 | 2.17 |
| 391.47 | 1.49 | 1.49 |
| 604.75 | 3.59 | 3.59 |
| 336.39 | 1.63 | 1.63 |
| 377.45 | 1.10 | 1.10 |
| 363.42 | 0.59 | 0.59 |
| 385.42 | 1.29 | 1.29 |
| 322.37 | 1.24 | 1.24 |
| 351.41 | 0.57 | 0.57 |
| 371.40 | 1.48 | 1.48 |
| 364.45 | 2.56 | 2.56 |
| 378.47 | 2.95 | 2.95 |
| 390.48 | 2.95 | 2.95 |
| 405.50 | 1.88 | 1.88 |
| 427.51 | 1.94 | 1.94 |
| 362.43 | 2.17 | 2.17 |
| 371.40 | 1.48 | 1.48 |
| 365.43 | 0.96 | 0.96 |
| 410.47 | 2.78 | 2.78 |
| 362.43 | 2.17 | 2.17 |
| 604.75 | 3.59 | 3.59 |
| 396.45 | 2.32 | 2.32 |
| 530.67 | 2.56 | 2.56 |
| 405.50 | 1.88 | 1.88 |
| 434.58 | 4.51 | 4.51 |
| 377.45 | 1.25 | 1.25 |
| 363.42 | 0.59 | 0.59 |
| 356.38 | 1.90 | 1.90 |
| 350.42 | 2.02 | 2.02 |
| 336.39 | 1.63 | 1.63 |
| 504.63 | 2.02 | 2.02 |
| 349.39 | 0.19 | 0.19 |
| 516.73 | 6.62 | 6.62 |
| 376.46 | 2.56 | 2.56 |