Basic Information
ID: ALA4628266
Type: Binding
Description: Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide pre-incubated for 60 mins followed by incubation with substrate for 30 mins measured by RapidFire/MS assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4628266
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 511.47 | 5.45 | 5.45 |
| 525.49 | 5.84 | 5.84 |
| 568.44 | 6.57 | 6.57 |
| 576.54 | 6.86 | 6.86 |
| 608.74 | 5.03 | 5.03 |
| 528.49 | 6.27 | 6.27 |
| 582.58 | 7.59 | 7.59 |
| 607.75 | 5.63 | 5.63 |
| 635.80 | 6.41 | 6.41 |
| 682.66 | 6.80 | 6.80 |
| 606.72 | 4.78 | 4.78 |
| 617.59 | 6.64 | 6.64 |
| 644.69 | 5.79 | 5.79 |
| 683.69 | 7.65 | 7.65 |
| 608.74 | 5.03 | 5.03 |
| 500.44 | 5.64 | 5.64 |
| 592.54 | 6.44 | 6.44 |