Basic Information
ID: ALA4628341
Type: Binding
Description: Inhibition of recombinant HIV1 integrase expressed in Escherichia coli Rosetta assessed as reduction in 3' end processing activity using [32P]-labelled U5B/U5A DNA as substrate measured after 2 hrs by polyacrylamide gel electrophoresis method
Organism: Human immunodeficiency virus 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4628341
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 889.09 | 3.58 | 3.58 |
| 949.14 | 3.44 | 3.44 |
| 917.14 | 4.36 | 4.36 |
| 945.19 | 5.14 | 5.14 |
| 1005.25 | ||
| 973.25 | 5.92 | 5.92 |
| 977.19 | 4.22 | 4.22 |
| 1033.30 |