Basic Information
ID: ALA4628556
Type: Binding
Description: Induction of CRBN-mediated pLOC-ePL-tagged aiolos (unknown origin) degradation in human DF15 cells assessed as minimum protein remaining up to 10 uM incubated for 4 hrs by luminescence based beta-galactosidase enzyme fragmentation complementation assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4628556
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 273.25 | -0.33 | -0.33 |
| 259.26 | 0.03 | 0.03 |
| 560.60 | 3.63 | 3.63 |
| 543.60 | 2.88 | 2.88 |
| 574.58 | 3.27 | 3.27 |
| 559.07 | 4.00 | 4.00 |
| 607.49 | 4.30 | 4.30 |
| 567.62 | 3.36 | 3.36 |
| 542.61 | 3.49 | 3.49 |
| 350.37 | 2.03 | 2.03 |
| 568.63 | 1.84 | 1.84 |
| 542.61 | 3.49 | 3.49 |
| 542.61 | 3.49 | 3.49 |
| 515.53 | 3.80 | 3.80 |
| 462.55 | 1.77 | 1.77 |
| 490.60 | 2.55 | 2.55 |
| 607.49 | 4.30 | 4.30 |
| 525.61 | 2.74 | 2.74 |
| 550.62 | 2.62 | 2.62 |
| 593.51 | 4.66 | 4.66 |
| 574.63 | 4.02 | 4.02 |
| 461.56 | 3.26 | 3.26 |
| 573.05 | 3.64 | 3.64 |
| 556.59 | 3.13 | 3.13 |
| 607.49 | 4.18 | 4.18 |
| 574.63 | 3.97 | 3.97 |
| 574.58 | 3.27 | 3.27 |
| 560.60 | 3.63 | 3.63 |
| 560.60 | 3.63 | 3.63 |
| 559.62 | 3.66 | 3.66 |
| 489.62 | 3.89 | 3.89 |
| 475.59 | 3.65 | 3.65 |
| 483.52 | 3.26 | 3.26 |
| 554.65 | 3.36 | 3.36 |
| 560.60 | 3.63 | 3.63 |
| 524.62 | 3.35 | 3.35 |
| 574.63 | 4.02 | 4.02 |
| 567.62 | 3.36 | 3.36 |
| 556.59 | 3.13 | 3.13 |