Basic Information
ID: ALA4628627
Type: Functional
Description: Potency index, ratio of lapatinib IC50 to test compound IC50 for antiproliferative activity against human NCI-H1975 cells harboring EGFR L858R/T790M mutant assessed as cell growth inhibition measured after 72 hrs by MTT assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H1975
Target: NCI-H1975(ALA614348)
Document: ALA4627322
Potency index, ratio of lapatinib IC50 to test compound IC50 for antiproliferative activity against human NCI-H1975 cells harboring EGFR L858R/T790M mutant assessed as cell growth inhibition measured after 72 hrs by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4628627
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 602.11 | 6.76 | 6.76 |
| 574.06 | 6.12 | 6.12 |
| 576.07 | 6.37 | 6.37 |