Basic Information
ID: ALA4628632
Type: Binding
Description: Potency index, ratio of erlotinib IC50 to test compound IC50 for inhibition of HER2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition measured after 40 mins in presence of ATP by caliper mobility shift assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Receptor protein-tyrosine kinase erbB-2(ALA1824)
Document: ALA4627322
Potency index, ratio of erlotinib IC50 to test compound IC50 for inhibition of HER2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition measured after 40 mins in presence of ATP by caliper mobility shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4628632
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 574.06 | 6.12 | 6.12 |
| 576.07 | 6.37 | 6.37 |