Assay Report Card

Basic Information

ID: ALA4630151

Type: ADME

Description: Positive allosteric modulation of recombinant rat GluN1a/GluN2A receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutamate-induced channel current at 10 to 30 uM by two-electrode voltage clamp method relative to control

Organism: Rattus norvegicus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
501.505.555.55
437.925.185.18
480.006.206.20
499.536.326.32
449.525.445.44
465.985.955.95
499.536.216.21
479.504.664.66
394.432.532.53
413.935.235.23
413.935.235.23
397.864.764.76
480.006.096.09
430.434.684.68
429.995.765.76
472.464.944.94
419.955.295.29
430.434.794.79
465.985.845.84
396.874.434.43
397.424.384.38
430.434.794.79
415.492.872.87
467.955.075.07
430.434.794.79
428.944.934.93
395.383.453.45
430.434.684.68
473.985.255.25
446.495.485.48
380.423.803.80
456.544.934.93
407.905.175.17
395.383.773.77
398.503.163.16
423.434.554.55
411.893.903.90
396.874.434.43
355.433.623.62
396.874.434.43
472.464.944.94
443.955.245.24
430.434.684.68
473.454.334.33
449.525.335.33
437.925.065.06
380.423.803.80