Basic Information
ID: ALA4630152
Type: ADME
Description: Positive allosteric modulation of recombinant rat GluN1a/GluN2B receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutamate-induced channel current at 10 to 30 uM by two-electrode voltage clamp method relative to control
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4630152
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 501.50 | 5.55 | 5.55 |
| 437.92 | 5.18 | 5.18 |
| 480.00 | 6.20 | 6.20 |
| 499.53 | 6.32 | 6.32 |
| 449.52 | 5.44 | 5.44 |
| 465.98 | 5.95 | 5.95 |
| 499.53 | 6.21 | 6.21 |
| 479.50 | 4.66 | 4.66 |
| 394.43 | 2.53 | 2.53 |
| 413.93 | 5.23 | 5.23 |
| 413.93 | 5.23 | 5.23 |
| 397.86 | 4.76 | 4.76 |
| 480.00 | 6.09 | 6.09 |
| 430.43 | 4.68 | 4.68 |
| 429.99 | 5.76 | 5.76 |
| 472.46 | 4.94 | 4.94 |
| 419.95 | 5.29 | 5.29 |
| 430.43 | 4.79 | 4.79 |
| 465.98 | 5.84 | 5.84 |
| 396.87 | 4.43 | 4.43 |
| 397.42 | 4.38 | 4.38 |
| 430.43 | 4.79 | 4.79 |
| 415.49 | 2.87 | 2.87 |
| 467.95 | 5.07 | 5.07 |
| 430.43 | 4.79 | 4.79 |
| 428.94 | 4.93 | 4.93 |
| 395.38 | 3.45 | 3.45 |
| 430.43 | 4.68 | 4.68 |
| 473.98 | 5.25 | 5.25 |
| 446.49 | 5.48 | 5.48 |
| 380.42 | 3.80 | 3.80 |
| 456.54 | 4.93 | 4.93 |
| 407.90 | 5.17 | 5.17 |
| 395.38 | 3.77 | 3.77 |
| 398.50 | 3.16 | 3.16 |
| 423.43 | 4.55 | 4.55 |
| 411.89 | 3.90 | 3.90 |
| 396.87 | 4.43 | 4.43 |
| 355.43 | 3.62 | 3.62 |
| 396.87 | 4.43 | 4.43 |
| 472.46 | 4.94 | 4.94 |
| 443.95 | 5.24 | 5.24 |
| 430.43 | 4.68 | 4.68 |
| 473.45 | 4.33 | 4.33 |
| 449.52 | 5.33 | 5.33 |
| 437.92 | 5.06 | 5.06 |
| 380.42 | 3.80 | 3.80 |