Basic Information
ID: ALA4630441
Type: Binding
Description: Antagonist activity at CCR4 in human CCRF-CEM cells assessed as inhibition of CCL22-mediated chemotaxis preincubated for 30 mins followed by CCL22 addition and measured after 60 mins in presence of 100% human serum by CellTiter-Glo assay
Organism: Homo sapiens
Cell type: CCRF-CEM
Activity Charts
Bioactivity
Activity Types for Assay ALA4630441
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 532.48 | 3.24 | 3.24 |
| 509.45 | 4.68 | 4.68 |
| 551.54 | 4.24 | 4.24 |
| 489.45 | 4.19 | 4.19 |
| 594.61 | 4.53 | 4.53 |
| 519.43 | 3.58 | 3.58 |
| 500.43 | 3.75 | 3.75 |
| 546.50 | 3.58 | 3.58 |
| 531.49 | 5.06 | 5.06 |
| 528.44 | 4.24 | 4.24 |
| 536.47 | 4.69 | 4.69 |
| 516.48 | 4.07 | 4.07 |
| 552.43 | 5.71 | 5.71 |
| 530.50 | 4.34 | 4.34 |
| 546.50 | 4.56 | 4.56 |
| 503.48 | 4.58 | 4.58 |
| 518.45 | 2.98 | 2.98 |
| 517.46 | 4.67 | 4.67 |
| 552.53 | 3.49 | 3.49 |
| 495.42 | 4.29 | 4.29 |
| 541.45 | 6.15 | 6.15 |
| 514.42 | 3.85 | 3.85 |
| 558.56 | 4.97 | 4.97 |
| 565.57 | 4.63 | 4.63 |
| 566.56 | 3.75 | 3.75 |