Basic Information
ID: ALA4630442
Type: Functional
Description: Antagonist activity at human CCR4 expressed in rat chem-5 cells assessed as inhibition of CCL22-induced calcium flux measured at 2.5 secs time interval for 45 secs by calcium 6 dye-based FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4630442
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 532.48 | 3.24 | 3.24 |
| 509.45 | 4.68 | 4.68 |
| 551.54 | 4.24 | 4.24 |
| 489.45 | 4.19 | 4.19 |
| 419.36 | 4.05 | 4.05 |
| 594.61 | 4.53 | 4.53 |
| 519.43 | 3.58 | 3.58 |
| 500.43 | 3.75 | 3.75 |
| 546.50 | 3.58 | 3.58 |
| 531.49 | 5.06 | 5.06 |
| 528.44 | 4.24 | 4.24 |
| 536.47 | 4.69 | 4.69 |
| 516.48 | 4.07 | 4.07 |
| 552.43 | 5.71 | 5.71 |
| 530.50 | 4.34 | 4.34 |
| 546.50 | 4.56 | 4.56 |
| 445.40 | 4.73 | 4.73 |
| 503.48 | 4.58 | 4.58 |
| 552.53 | 3.49 | 3.49 |
| 518.45 | 2.98 | 2.98 |
| 531.49 | 4.76 | 4.76 |
| 517.46 | 4.67 | 4.67 |
| 552.53 | 3.49 | 3.49 |
| 495.42 | 4.29 | 4.29 |
| 541.45 | 6.15 | 6.15 |
| 514.42 | 3.85 | 3.85 |
| 558.56 | 4.97 | 4.97 |
| 473.45 | 5.22 | 5.22 |
| 565.57 | 4.63 | 4.63 |
| 566.56 | 3.75 | 3.75 |
| 552.53 | 3.49 | 3.49 |