Basic Information
ID: ALA4630452
Type: ADME
Description: Ratio of IC50 for time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam hydrochloride as substrate in presence of NADPH to IC50 for time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam hydrochloride as substrate absence of NADPH
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4630452
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 489.45 | 4.19 | 4.19 |
| 500.43 | 3.75 | 3.75 |