Basic Information
ID: ALA4651365
Type: Functional
Description: Concentration required to kill 50% of 21 day old worms 5 days after drug treatment.
Organism: Schistosoma mansoni
Strain: Puerto Rican
Activity Charts
Bioactivity
Activity Types for Assay ALA4651365
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.41 | 2.53 | 2.53 |
| 427.51 | 2.87 | 2.87 |
| 314.39 | 4.58 | 4.58 |
| 349.37 | 4.22 | 4.22 |
| 291.31 | 2.50 | 2.50 |
| 359.43 | 4.34 | 4.34 |
| 319.34 | 4.21 | 4.21 |
| 400.49 | 3.22 | 3.22 |
| 332.36 | 3.48 | 3.48 |
| 345.40 | 4.47 | 4.47 |
| 347.39 | 4.99 | 4.99 |
| 343.43 | 5.20 | 5.20 |
| 321.34 | 1.96 | 1.96 |
| 343.43 | 5.20 | 5.20 |
| 251.33 | 3.83 | 3.83 |
| 439.42 | 6.22 | 6.22 |
| 434.50 | 2.61 | 2.61 |
| 344.37 | 3.73 | 3.73 |
| 373.46 | 5.00 | 5.00 |
| 303.37 | 3.91 | 3.91 |
| 389.45 | 4.87 | 4.87 |
| 457.41 | 6.36 | 6.36 |
| 398.39 | 5.26 | 5.26 |
| 388.43 | 3.44 | 3.44 |
| 360.42 | 3.54 | 3.54 |
| 455.42 | 5.88 | 5.88 |
| 356.38 | 3.95 | 3.95 |
| 480.55 | 3.10 | 3.10 |
| 417.46 | 5.90 | 5.90 |
| 409.49 | 5.10 | 5.10 |
| 505.40 | 6.75 | 6.75 |
| 391.30 | 5.07 | 5.07 |
| 291.31 | 2.50 | 2.50 |
| 345.41 | 4.08 | 4.08 |
| 360.42 | 4.25 | 4.25 |
| 389.41 | 3.85 | 3.85 |
| 380.43 | 3.14 | 3.14 |
| 371.44 | 4.79 | 4.79 |
| 391.43 | 4.10 | 4.10 |
| 418.50 | 2.91 | 2.91 |
| 347.39 | 5.03 | 5.03 |
| 267.33 | 3.49 | 3.49 |
| 358.40 | 3.43 | 3.43 |
| 365.82 | 4.73 | 4.73 |
| 405.33 | 5.37 | 5.37 |
| 370.33 | 4.49 | 4.49 |
| 362.39 | 3.48 | 3.48 |
| 373.41 | 4.02 | 4.02 |
| 443.38 | 5.80 | 5.80 |
| 389.45 | 4.87 | 4.87 |
| 443.50 | 6.61 | 6.61 |
| 331.38 | 3.64 | 3.64 |
| 382.39 | 5.60 | 5.60 |
| 293.33 | 3.25 | 3.25 |
| 329.40 | 4.89 | 4.89 |
| 427.43 | 5.92 | 5.92 |
| 487.40 | 7.18 | 7.18 |
| 372.32 | 5.53 | 5.53 |
| 483.32 | 6.26 | 6.26 |
| 360.42 | 4.25 | 4.25 |
| 363.38 | 2.88 | 2.88 |
| 344.42 | 4.55 | 4.55 |
| 369.43 | 4.73 | 4.73 |
| 342.45 | 4.65 | 4.65 |
| 466.32 | 5.51 | 5.51 |
| 403.49 | 4.36 | 4.36 |
| 369.43 | 4.73 | 4.73 |
| 317.40 | 3.92 | 3.92 |
| 353.39 | 4.16 | 4.16 |
| 348.36 | 3.18 | 3.18 |
| 359.39 | 3.84 | 3.84 |
| 397.40 | 6.09 | 6.09 |
| 450.52 | 3.09 | 3.09 |
| 341.37 | 3.66 | 3.66 |
| 346.39 | 3.66 | 3.66 |
| 533.33 | 6.89 | 6.89 |
| 291.31 | 2.50 | 2.50 |
| 360.42 | 4.25 | 4.25 |
| 455.39 | 6.11 | 6.11 |
| 318.34 | 2.47 | 2.47 |
| 469.42 | 6.50 | 6.50 |
| 439.42 | 6.22 | 6.22 |
| 369.35 | 5.10 | 5.10 |
| 440.40 | 5.62 | 5.62 |
| 463.38 | 6.26 | 6.26 |
| 359.43 | 4.86 | 4.86 |
| 437.34 | 5.77 | 5.77 |
| 367.41 | 4.01 | 4.01 |
| 405.33 | 5.37 | 5.37 |
| 479.36 | 6.42 | 6.42 |
| 431.49 | 6.46 | 6.46 |
| 347.39 | 5.03 | 5.03 |
| 344.42 | 4.59 | 4.59 |
| 319.37 | 3.57 | 3.57 |
| 349.37 | 4.31 | 4.31 |
| 372.39 | 3.35 | 3.35 |
| 321.34 | 2.80 | 2.80 |
| 333.40 | 3.58 | 3.58 |
| 332.36 | 3.48 | 3.48 |
| 346.39 | 3.78 | 3.78 |
| 341.37 | 3.66 | 3.66 |
| 400.36 | 4.49 | 4.49 |
| 318.34 | 3.17 | 3.17 |
| 359.31 | 3.52 | 3.52 |
| 441.31 | 5.95 | 5.95 |
| 328.42 | 4.77 | 4.77 |
| 433.38 | 6.19 | 6.19 |
| 457.41 | 6.36 | 6.36 |
| 423.44 | 6.19 | 6.19 |
| 389.46 | 4.87 | 4.87 |
| 433.38 | 6.19 | 6.19 |
| 392.48 | 3.83 | 3.83 |
| 362.39 | 3.48 | 3.48 |
| 318.34 | 2.47 | 2.47 |
| 413.40 | 5.36 | 5.36 |
| 353.43 | 5.06 | 5.06 |
| 359.43 | 4.64 | 4.64 |
| 415.39 | 6.05 | 6.05 |
| 333.40 | 3.62 | 3.62 |
| 497.35 | 6.34 | 6.34 |
| 445.42 | 6.06 | 6.06 |
| 383.45 | 4.74 | 4.74 |
| 359.43 | 4.90 | 4.90 |
| 306.33 | 3.37 | 3.37 |
| 330.35 | 2.87 | 2.87 |
| 356.31 | 4.18 | 4.18 |
| 373.31 | 4.93 | 4.93 |
| 457.41 | 6.36 | 6.36 |
| 347.35 | 4.11 | 4.11 |
| 427.43 | 5.92 | 5.92 |
| 362.39 | 3.48 | 3.48 |
| 499.32 | 6.14 | 6.14 |
| 344.37 | 2.80 | 2.80 |
| 358.40 | 3.47 | 3.47 |
| 473.32 | 6.15 | 6.15 |
| 515.34 | 6.75 | 6.75 |
| 343.43 | 4.68 | 4.68 |
| 358.45 | 4.31 | 4.31 |
| 329.36 | 3.97 | 3.97 |
| 359.43 | 4.86 | 4.86 |
| 465.33 | 6.12 | 6.12 |
| 341.37 | 3.66 | 3.66 |
| 331.38 | 4.08 | 4.08 |
| 449.35 | 6.08 | 6.08 |
| 330.39 | 3.53 | 3.53 |
| 354.41 | 4.72 | 4.72 |
| 465.33 | 6.12 | 6.12 |
| 389.76 | 5.44 | 5.44 |
| 499.36 | 6.72 | 6.72 |
| 344.42 | 4.55 | 4.55 |
| 331.38 | 3.56 | 3.56 |
| 345.40 | 4.56 | 4.56 |
| 353.43 | 5.06 | 5.06 |
| 354.41 | 4.72 | 4.72 |
| 361.40 | 3.65 | 3.65 |
| 373.31 | 4.93 | 4.93 |
| 503.35 | 6.45 | 6.45 |
| 327.35 | 3.65 | 3.65 |
| 314.39 | 4.58 | 4.58 |
| 463.38 | 6.47 | 6.47 |
| 398.38 | 5.71 | 5.71 |
| 333.40 | 3.58 | 3.58 |
| 343.43 | 5.20 | 5.20 |
| 495.37 | 5.82 | 5.82 |
| 450.32 | 5.96 | 5.96 |
| 371.40 | 3.96 | 3.96 |
| 359.43 | 4.90 | 4.90 |
| 455.39 | 6.11 | 6.11 |
| 503.30 | 5.28 | 5.28 |
| 385.43 | 3.97 | 3.97 |
| 291.31 | 2.50 | 2.50 |
| 347.35 | 4.11 | 4.11 |
| 389.45 | 4.87 | 4.87 |
| 314.39 | 4.58 | 4.58 |
| 317.40 | 3.92 | 3.92 |
| 318.34 | 3.17 | 3.17 |
| 495.45 | 7.61 | 7.61 |
| 361.40 | 4.09 | 4.09 |
| 354.37 | 4.42 | 4.42 |
| 349.37 | 4.22 | 4.22 |
| 344.42 | 4.43 | 4.43 |
| 515.46 | 8.00 | 8.00 |
| 343.43 | 5.20 | 5.20 |
| 331.38 | 3.38 | 3.38 |
| 401.36 | 5.49 | 5.49 |
| 507.41 | 7.72 | 7.72 |
| 354.42 | 4.46 | 4.46 |
| 344.42 | 3.83 | 3.83 |
| 494.22 | 6.00 | 6.00 |
| 399.37 | 5.10 | 5.10 |
| 347.39 | 4.99 | 4.99 |
| 305.34 | 3.11 | 3.11 |
| 481.33 | 6.00 | 6.00 |
| 373.31 | 4.93 | 4.93 |
| 430.51 | 3.23 | 3.23 |
| 305.34 | 2.81 | 2.81 |
| 387.34 | 5.24 | 5.24 |
| 329.40 | 4.89 | 4.89 |
| 335.79 | 4.73 | 4.73 |
| 451.37 | 6.33 | 6.33 |
| 360.42 | 4.25 | 4.25 |
| 359.43 | 4.90 | 4.90 |
| 452.36 | 5.75 | 5.75 |
| 391.50 | 4.59 | 4.59 |
| 398.39 | 5.26 | 5.26 |
| 358.40 | 3.47 | 3.47 |
| 439.42 | 6.22 | 6.22 |
| 343.39 | 4.01 | 4.01 |
| 327.35 | 3.65 | 3.65 |
| 373.46 | 5.20 | 5.20 |
| 451.37 | 6.33 | 6.33 |
| 406.51 | 4.56 | 4.56 |
| 427.43 | 5.92 | 5.92 |
| 473.41 | 6.02 | 6.02 |
| 332.36 | 3.48 | 3.48 |
| 373.46 | 5.20 | 5.20 |
| 375.43 | 4.57 | 4.57 |
| 359.43 | 4.90 | 4.90 |
| 371.40 | 3.96 | 3.96 |
| 359.43 | 4.34 | 4.34 |
| 408.48 | 3.50 | 3.50 |
| 451.37 | 6.33 | 6.33 |
| 347.37 | 3.79 | 3.79 |
| 451.45 | 6.09 | 6.09 |
| 491.43 | 7.83 | 7.83 |
| 344.42 | 4.59 | 4.59 |
| 429.47 | 6.22 | 6.22 |
| 345.41 | 3.99 | 3.99 |
| 326.36 | 3.94 | 3.94 |
| 343.43 | 4.68 | 4.68 |
| 437.34 | 5.77 | 5.77 |
| 302.34 | 3.47 | 3.47 |
| 399.37 | 5.10 | 5.10 |
| 344.42 | 4.59 | 4.59 |
| 329.40 | 4.89 | 4.89 |
| 449.84 | 6.70 | 6.70 |
| 513.44 | 7.75 | 7.75 |
| 345.40 | 4.56 | 4.56 |
| 359.43 | 4.90 | 4.90 |
| 389.45 | 4.87 | 4.87 |
| 293.33 | 2.91 | 2.91 |
| 331.38 | 3.30 | 3.30 |
| 394.46 | 3.02 | 3.02 |
| 366.40 | 2.57 | 2.57 |
| 360.42 | 4.25 | 4.25 |
| 349.37 | 4.22 | 4.22 |
| 375.43 | 4.48 | 4.48 |
| 377.42 | 5.00 | 5.00 |
| 455.33 | 6.01 | 6.01 |
| 469.42 | 6.50 | 6.50 |
| 469.37 | 5.25 | 5.25 |
| 531.35 | 6.09 | 6.09 |
| 362.39 | 3.48 | 3.48 |
| 361.40 | 3.57 | 3.57 |
| 507.41 | 5.69 | 5.69 |
| 373.41 | 4.02 | 4.02 |
| 491.31 | 6.31 | 6.31 |
| 425.41 | 5.67 | 5.67 |
| 423.32 | 5.51 | 5.51 |
| 457.41 | 6.36 | 6.36 |
| 487.35 | 6.40 | 6.40 |
| 359.43 | 4.86 | 4.86 |