Basic Information
ID: ALA4651370
Type: Functional
Description: Percentage of worms remaining following treatment of female CD1 mice infected with S. mansoni worms (21 day old - juvenile or 42 day old - adult) with compound by oral gavage. Worms were recovered by portal perfusion with citrate saline 8-14 days post treatment and counted. Percentages are from a mean of 5 or 6 animals.
Organism: Mus musculus
Strain: CD1
Activity Charts
Bioactivity
Activity Types for Assay ALA4651370
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.41 | 2.53 | 2.53 |
| 443.38 | 5.80 | 5.80 |
| 483.32 | 6.26 | 6.26 |
| 533.33 | 6.89 | 6.89 |
| 455.39 | 6.11 | 6.11 |
| 457.41 | 6.36 | 6.36 |
| 457.41 | 6.36 | 6.36 |
| 515.34 | 6.75 | 6.75 |
| 449.35 | 6.08 | 6.08 |
| 451.37 | 6.33 | 6.33 |
| 429.47 | 6.22 | 6.22 |
| 487.35 | 6.40 | 6.40 |