Basic Information
ID: ALA4651405
Type: Toxicity
Description: Toxicity CC50 against VERO-E6 cells determined at 48 hours by high content imaging (same conditions as IC50 assay without exposure to 0.01 MOI SARS CoV-2 virus)
Organism: Chlorocebus sabaeus
Cell type: Vero C1008
Activity Charts
Bioactivity
Activity Types for Assay ALA4651405
CC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 3.93 | 3.93 |
| 391.56 | 6.86 | 6.86 |
| 314.86 | 4.53 | 4.53 |
| 407.51 | 4.95 | 4.95 |
| 263.38 | 3.83 | 3.83 |
| 302.37 | 3.57 | 3.57 |
| 395.48 | 3.22 | 3.22 |
| 370.59 | 5.89 | 5.89 |
| 319.88 | 4.81 | 4.81 |
| 329.37 | 3.33 | 3.33 |
| 468.38 | 4.09 | 4.09 |
| 426.56 | 4.13 | 4.13 |
| 310.35 | 3.14 | 3.14 |
| 284.43 | 4.24 | 4.24 |
| 670.86 | 3.09 | 3.09 |
| 567.80 | 4.75 | 4.75 |
| 471.69 | 6.45 | 6.45 |
| 381.91 | 4.30 | 4.30 |
| 284.43 | 4.24 | 4.24 |
| 405.44 | 2.36 | 2.36 |
| 309.45 | 4.29 | 4.29 |
| 328.48 | 4.50 | 4.50 |
| 263.38 | 4.30 | 4.30 |
| 329.49 | 5.43 | 5.43 |
| 417.55 | 4.18 | 4.18 |
| 331.87 | 4.88 | 4.88 |
| 425.57 | 6.08 | 6.08 |
| 353.51 | 4.66 | 4.66 |
| 267.33 | 2.65 | 2.65 |
| 406.48 | 3.74 | 3.74 |
| 437.53 | 4.31 | 4.31 |
| 628.81 | 4.33 | 4.33 |
| 373.50 | 5.79 | 5.79 |
| 440.61 | 3.91 | 3.91 |
| 489.41 | 5.50 | 5.50 |
| 326.47 | 4.44 | 4.44 |
| 477.05 | 5.09 | 5.09 |
| 456.59 | 5.94 | 5.94 |
| 458.58 | 5.35 | 5.35 |
| 475.58 | 5.31 | 5.31 |
| 311.81 | 4.97 | 4.97 |
| 368.52 | 5.11 | 5.11 |
| 226.23 | 2.23 | 2.23 |
| 523.97 | 7.53 | 7.53 |
| 1202.63 | ||
| 543.53 | 0.00 | 0.00 |
| 315.87 | 5.19 | 5.19 |
| 400.98 | 4.24 | 4.24 |
| 450.50 | 5.92 | 5.92 |
| 720.96 | 5.91 | 5.91 |
| 209.25 | 2.55 | 2.55 |
| 493.62 | 4.59 | 4.59 |
| 372.55 | 6.26 | 6.26 |
| 552.55 | 6.37 | 6.37 |
| 303.83 | 4.63 | 4.63 |
| 705.65 | 5.58 | 5.58 |
| 342.44 | 1.01 | 1.01 |
| 322.48 | 4.63 | 4.63 |
| 341.88 | 5.07 | 5.07 |
| 872.89 | 6.67 | 6.67 |
| 332.31 | 3.67 | 3.67 |
| 343.90 | 5.10 | 5.10 |
| 293.32 | 4.03 | 4.03 |
| 411.57 | 3.49 | 3.49 |
| 343.47 | 3.49 | 3.49 |
| 491.63 | 5.75 | 5.75 |
| 500.43 | 8.64 | 8.64 |
| 448.39 | 4.86 | 4.86 |
| 363.46 | 3.39 | 3.39 |
| 313.42 | 1.13 | 1.13 |
| 295.45 | 4.68 | 4.68 |
| 368.39 | 3.85 | 3.85 |
| 562.72 | 5.03 | 5.03 |
| 467.65 | 3.24 | 3.24 |
| 382.55 | 4.81 | 4.81 |
| 604.70 | 3.54 | 3.54 |
| 397.48 | 4.34 | 4.34 |
| 443.64 | 3.47 | 3.47 |
| 378.41 | 0.49 | 0.49 |
| 297.42 | 4.63 | 4.63 |
| 415.57 | 4.11 | 4.11 |
| 292.21 | 4.79 | 4.79 |
| 293.43 | 4.68 | 4.68 |
| 291.44 | 3.47 | 3.47 |
| 608.69 | 4.17 | 4.17 |
| 532.47 | 4.46 | 4.46 |
| 310.19 | 3.67 | 3.67 |
| 457.61 | 5.61 | 5.61 |
| 360.89 | 3.58 | 3.58 |
| 317.23 | 3.84 | 3.84 |
| 426.56 | 3.96 | 3.96 |
| 622.76 | 7.16 | 7.16 |
| 557.05 | 5.93 | 5.93 |
| 350.46 | 1.96 | 1.96 |
| 556.77 | 7.05 | 7.05 |
| 312.37 | 3.18 | 3.18 |
| 356.60 | 4.81 | 4.81 |
| 700.79 | 4.57 | 4.57 |
| 152.12 | -0.96 | -0.96 |
| 365.50 | 4.01 | 4.01 |
| 307.44 | 4.42 | 4.42 |
| 304.32 | 2.98 | 2.98 |
| 475.68 | 4.02 | 4.02 |
| 376.37 | -1.72 | -1.72 |
| 335.88 | 3.78 | 3.78 |
| 391.56 | 5.97 | 5.97 |
| 558.73 | 4.47 | 4.47 |
| 455.55 | 4.40 | 4.40 |
| 410.58 | 4.98 | 4.98 |
| 512.57 | 5.74 | 5.74 |
| 317.34 | 2.04 | 2.04 |
| 285.77 | 4.26 | 4.26 |
| 295.30 | 4.17 | 4.17 |
| 521.67 | 3.56 | 3.56 |
| 974.63 | 8.83 | 8.83 |
| 400.56 | 6.32 | 6.32 |
| 778.95 | 4.75 | 4.75 |
| 328.48 | 4.50 | 4.50 |
| 337.57 | 5.56 | 5.56 |
| 446.64 | 3.18 | 3.18 |
| 507.64 | 5.94 | 5.94 |
| 510.48 | -0.17 | -0.17 |
| 594.71 | 6.56 | 6.56 |
| 532.57 | 4.46 | 4.46 |
| 269.39 | 3.66 | 3.66 |
| 183.25 | 1.13 | 1.13 |
| 466.96 | 3.92 | 3.92 |
| 296.44 | 4.24 | 4.24 |
| 929.16 | 8.07 | 8.07 |
| 433.04 | 6.54 | 6.54 |
| 461.56 | 5.16 | 5.16 |
| 425.60 | 3.88 | 3.88 |
| 309.48 | 5.02 | 5.02 |
| 293.41 | 3.18 | 3.18 |
| 421.50 | 4.55 | 4.55 |
| 618.83 | 4.27 | 4.27 |
| 228.29 | 2.70 | 2.70 |
| 360.91 | 5.34 | 5.34 |
| 424.55 | 3.97 | 3.97 |
| 314.86 | 4.07 | 4.07 |
| 261.37 | 4.21 | 4.21 |
| 310.35 | 3.14 | 3.14 |
| 362.45 | 5.10 | 5.10 |
| 275.39 | 3.53 | 3.53 |
| 604.53 | 5.27 | 5.27 |
| 616.62 | 6.65 | 6.65 |
| 294.40 | 3.12 | 3.12 |
| 339.51 | 3.93 | 3.93 |
| 471.55 | 5.42 | 5.42 |
| 450.35 | 5.04 | 5.04 |
| 410.30 | 4.41 | 4.41 |
| 328.80 | 4.13 | 4.13 |
| 588.49 | 7.50 | 7.50 |
| 392.50 | 5.08 | 5.08 |
| 738.89 | 6.22 | 6.22 |
| 519.57 | 5.58 | 5.58 |
| 326.44 | 3.40 | 3.40 |
| 320.83 | 1.93 | 1.93 |
| 598.17 | 5.83 | 5.83 |
| 505.57 | 4.21 | 4.21 |
| 433.58 | 4.72 | 4.72 |
| 672.74 | 4.55 | 4.55 |
| 442.60 | 5.07 | 5.07 |
| 479.07 | 4.74 | 4.74 |
| 419.52 | 5.19 | 5.19 |
| 415.90 | 4.11 | 4.11 |
| 284.44 | 4.31 | 4.31 |
| 314.45 | 4.25 | 4.25 |
| 305.43 | 4.17 | 4.17 |
| 303.83 | 4.18 | 4.18 |
| 446.64 | 4.12 | 4.12 |
| 435.01 | 5.57 | 5.57 |
| 434.62 | 6.40 | 6.40 |
| 395.59 | 4.45 | 4.45 |
| 296.37 | 4.54 | 4.54 |
| 452.62 | 3.79 | 3.79 |
| 444.00 | 4.68 | 4.68 |
| 320.85 | 3.38 | 3.38 |
| 572.52 | 4.64 | 4.64 |
| 517.07 | 6.53 | 6.53 |
| 415.53 | 5.23 | 5.23 |
| 608.74 | 6.86 | 6.86 |
| 762.91 | 6.86 | 6.86 |
| 470.61 | 5.91 | 5.91 |
| 392.55 | 4.48 | 4.48 |
| 478.59 | 4.50 | 4.50 |
| 499.62 | 4.51 | 4.51 |
| 492.58 | 4.01 | 4.01 |
| 434.55 | 2.80 | 2.80 |
| 446.56 | 4.18 | 4.18 |
| 473.58 | 6.32 | 6.32 |
| 555.64 | 7.94 | 7.94 |
| 506.66 | 4.88 | 4.88 |
| 402.97 | 5.76 | 5.76 |
| 463.56 | 3.95 | 3.95 |
| 602.59 | 2.31 | 2.31 |
| 337.85 | 3.94 | 3.94 |
| 480.59 | 3.78 | 3.78 |
| 407.45 | 4.83 | 4.83 |
| 434.53 | 4.60 | 4.60 |
| 534.61 | 6.97 | 6.97 |
| 448.60 | 5.74 | 5.74 |
| 249.74 | 3.90 | 3.90 |
| 287.41 | 3.39 | 3.39 |
| 335.88 | 3.78 | 3.78 |
| 634.73 | 4.57 | 4.57 |
| 756.00 | 5.22 | 5.22 |
| 330.34 | 4.08 | 4.08 |
| 666.72 | 4.70 | 4.70 |
| 578.66 | 4.16 | 4.16 |
| 319.40 | 4.71 | 4.71 |
| 297.37 | 3.56 | 3.56 |
| 443.59 | 6.22 | 6.22 |
| 369.51 | 4.71 | 4.71 |
| 534.61 | 6.97 | 6.97 |
| 596.91 | 4.49 | 4.49 |
| 364.53 | 5.23 | 5.23 |
| 310.47 | 4.63 | 4.63 |
| 347.42 | 5.64 | 5.64 |
| 538.45 | 4.19 | 4.19 |
| 335.88 | 3.78 | 3.78 |
| 590.80 | 5.84 | 5.84 |