Positive allosteric modulator activity at human mGlu4 receptor/Gqi5 assessed as maximum activity at 30 uM by calcium mobilization assay relative to gl...

Basic Information

ID: ALA4665921

Type: Functional

Description: Positive allosteric modulator activity at human mGlu4 receptor/Gqi5 assessed as maximum activity at 30 uM by calcium mobilization assay relative to glutamic acid

Format: BAO_0000019

Organism: Homo sapiens

Target:  Metabotropic glutamate receptor 4(ALA2736)

Document:  ALA4665621

Positive allosteric modulator activity at human mGlu4 receptor/Gqi5 assessed as maximum activity at 30 uM by calcium mobilization assay relative to glutamic acid: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
341.383.653.65
366.434.864.86
412.425.175.17
345.414.134.13
359.443.003.00
330.403.853.85
301.354.134.13
366.384.104.10
332.414.104.10
345.413.823.82
289.343.813.81
330.404.214.21
333.403.673.67
260.303.853.85
329.294.274.27
291.312.552.55
311.304.194.19
357.344.924.92
341.383.743.74
261.293.253.25
330.273.663.66
277.292.542.54
355.414.054.05
409.384.674.67
327.353.443.44
261.293.253.25
344.424.244.24
329.294.274.27
334.383.313.31