Basic Information
ID: ALA4666136
Type: Binding
Description: Inhibition of rat DYRK1A kinase domain (1 to 499 residues) expressed in bacteria assessed as residual activity at 1 uM using KKISGRLSPIMTEQ as substrate in presence of [gamma-33P]ATP relative to control
Format: BAO_0000019
Organism: Rattus norvegicus
Target: Dual specificity tyrosine-phosphorylation-regulated kinase 1A(ALA5508)
Document: ALA4665625
Inhibition of rat DYRK1A kinase domain (1 to 499 residues) expressed in bacteria assessed as residual activity at 1 uM using KKISGRLSPIMTEQ as substrate in presence of [gamma-33P]ATP relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4666136
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.29 | 3.75 | 3.75 |
| 324.39 | 1.50 | 1.50 |
| 310.41 | 2.51 | 2.51 |
| 367.41 | 1.75 | 1.75 |
| 272.31 | 3.43 | 3.43 |
| 354.41 | 3.23 | 3.23 |
| 338.42 | 1.89 | 1.89 |
| 340.39 | 2.84 | 2.84 |
| 337.43 | 1.42 | 1.42 |
| 282.35 | 1.73 | 1.73 |
| 352.40 | 2.98 | 2.98 |
| 322.42 | 2.66 | 2.66 |
| 296.38 | 2.12 | 2.12 |
| 338.37 | 2.59 | 2.59 |
| 225.25 | 1.80 | 1.80 |
| 354.37 | 1.83 | 1.83 |
| 326.36 | 2.45 | 2.45 |
| 351.46 | 1.81 | 1.81 |
| 322.42 | 2.66 | 2.66 |
| 352.40 | 2.98 | 2.98 |
| 255.24 | 2.13 | 2.13 |
| 366.43 | 3.37 | 3.37 |
| 312.33 | 2.06 | 2.06 |
| 381.44 | 2.14 | 2.14 |
| 336.44 | 3.05 | 3.05 |
| 368.40 | 2.22 | 2.22 |
| 308.39 | 2.27 | 2.27 |
| 324.43 | 2.90 | 2.90 |