Basic Information
ID: ALA4666308
Type: Functional
Description: Antibacterial activity against efflux pump d effect ive Escherichia coli JW5503 harbouring tolC mutant assessed as bacterial growth inhibition at 50 uM incubated for 24 hrs by CLSI protocol based broth microdilution assay relative to control
Organism: Escherichia coli
Strain: JW5503
Activity Charts
Bioactivity
Activity Types for Assay ALA4666308
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.33 | 3.96 | 3.96 |
| 436.30 | 4.39 | 4.39 |
| 348.21 | 2.53 | 2.53 |
| 505.79 | 2.83 | 2.83 |
| 555.42 | 4.08 | 4.08 |
| 352.18 | 4.06 | 4.06 |
| 390.25 | 2.57 | 2.57 |
| 426.07 | 3.05 | 3.05 |
| 519.81 | 3.22 | 3.22 |
| 420.27 | 2.33 | 2.33 |
| 456.33 | 2.78 | 2.78 |
| 583.47 | 4.86 | 4.86 |
| 658.34 | 4.47 | 4.47 |
| 569.44 | 4.47 | 4.47 |
| 431.33 | 4.14 | 4.14 |
| 597.50 | 4.95 | 4.95 |
| 533.84 | 3.30 | 3.30 |
| 406.25 | 2.25 | 2.25 |
| 491.76 | 2.44 | 2.44 |
| 470.31 | 3.11 | 3.11 |
| 597.50 | 4.95 | 4.95 |
| 498.39 | 5.21 | 5.21 |
| 644.32 | 4.38 | 4.38 |
| 545.18 | 3.02 | 3.02 |
| 580.66 | 2.74 | 2.74 |
| 583.47 | 4.86 | 4.86 |
| 569.44 | 4.17 | 4.17 |
| 533.84 | 3.30 | 3.30 |
| 583.47 | 4.56 | 4.56 |
| 408.24 | 3.92 | 3.92 |
| 505.79 | 2.53 | 2.53 |
| 353.17 | 2.15 | 2.15 |
| 519.81 | 3.22 | 3.22 |
| 351.19 | 3.14 | 3.14 |