Basic Information
ID: ALA4666432
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-tagged MNK2 (1 to 465 residues) expressed in baculovirus expression system using TATKSGSTTKNR as substrate preincubated for 10 mins followed by ATP addition and measured after 40 mins by luminescence based assay
Format: BAO_0000019
Organism: Homo sapiens
Target: MAP kinase signal-integrating kinase 2(ALA4204)
Document: ALA4665632
Inhibition of recombinant human N-terminal GST-tagged MNK2 (1 to 465 residues) expressed in baculovirus expression system using TATKSGSTTKNR as substrate preincubated for 10 mins followed by ATP addition and measured after 40 mins by luminescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4666432
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.39 | 1.63 | 1.63 |
| 339.40 | 2.24 | 2.24 |
| 451.53 | 1.72 | 1.72 |
| 338.41 | 2.96 | 2.96 |
| 342.40 | 1.58 | 1.58 |
| 325.37 | 2.05 | 2.05 |
| 377.40 | 2.93 | 2.93 |
| 324.38 | 2.66 | 2.66 |
| 352.40 | 1.87 | 1.87 |
| 324.38 | 2.66 | 2.66 |
| 408.51 | 3.04 | 3.04 |
| 338.41 | 2.96 | 2.96 |
| 340.39 | 1.63 | 1.63 |
| 409.49 | 1.46 | 1.46 |
| 340.39 | 1.63 | 1.63 |
| 494.64 | 2.12 | 2.12 |
| 325.37 | 2.05 | 2.05 |
| 325.37 | 2.05 | 2.05 |
| 325.37 | 2.05 | 2.05 |
| 325.37 | 2.05 | 2.05 |
| 340.39 | 1.63 | 1.63 |
| 423.52 | 1.80 | 1.80 |
| 324.38 | 2.66 | 2.66 |
| 339.40 | 2.24 | 2.24 |
| 338.41 | 2.96 | 2.96 |
| 423.52 | 2.21 | 2.21 |
| 480.62 | 1.73 | 1.73 |
| 423.52 | 1.98 | 1.98 |
| 410.48 | 1.89 | 1.89 |