Basic Information
ID: ALA4666933
Type: Binding
Description: Inhibition of JAK in human BEAS-2B cells assessed as reduction in IL13-induced STAT6 phosphorylation incubated for 1 hr followed by IL13 addition and measured after 15 mins by immunofluorescence assay
Organism: Homo sapiens
Cell type: BEAS-2B
Activity Charts
Bioactivity
Activity Types for Assay ALA4666933
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 352.79 | 3.04 | 3.04 |
| 387.23 | 3.69 | 3.69 |
| 382.81 | 3.04 | 3.04 |
| 352.79 | 3.13 | 3.13 |
| 286.33 | 2.32 | 2.32 |
| 432.53 | 3.50 | 3.50 |
| 380.37 | 2.91 | 2.91 |
| 399.86 | 4.08 | 4.08 |
| 396.24 | 4.65 | 4.65 |
| 384.78 | 2.74 | 2.74 |
| 419.78 | 3.21 | 3.21 |
| 449.21 | 3.74 | 3.74 |
| 384.40 | 3.53 | 3.53 |
| 396.84 | 2.57 | 2.57 |
| 404.76 | 3.63 | 3.63 |
| 382.81 | 3.27 | 3.27 |
| 420.38 | 4.13 | 4.13 |
| 383.80 | 2.67 | 2.67 |
| 428.79 | 3.61 | 3.61 |
| 410.34 | 2.85 | 2.85 |
| 382.81 | 2.53 | 2.53 |
| 398.88 | 3.76 | 3.76 |
| 386.77 | 3.17 | 3.17 |
| 422.75 | 3.77 | 3.77 |
| 374.36 | 2.26 | 2.26 |
| 392.85 | 3.91 | 3.91 |
| 422.75 | 3.77 | 3.77 |
| 370.32 | 2.97 | 2.97 |
| 398.37 | 3.54 | 3.54 |
| 384.35 | 3.28 | 3.28 |
| 418.79 | 3.93 | 3.93 |
| 404.76 | 3.86 | 3.86 |
| 394.82 | 3.57 | 3.57 |
| 496.21 | 3.58 | 3.58 |
| 418.79 | 3.93 | 3.93 |
| 418.79 | 3.64 | 3.64 |
| 420.83 | 4.34 | 4.34 |
| 404.76 | 4.73 | 4.73 |
| 421.82 | 4.59 | 4.59 |
| 368.78 | 2.74 | 2.74 |
| 382.81 | 3.42 | 3.42 |
| 396.84 | 3.28 | 3.28 |
| 395.33 | 2.84 | 2.84 |
| 387.23 | 3.69 | 3.69 |
| 382.81 | 3.27 | 3.27 |
| 421.82 | 4.59 | 4.59 |
| 420.76 | 3.33 | 3.33 |
| 422.75 | 3.92 | 3.92 |
| 404.76 | 3.86 | 3.86 |
| 404.76 | 3.63 | 3.63 |
| 410.87 | 3.82 | 3.82 |
| 386.77 | 3.17 | 3.17 |
| 393.83 | 3.94 | 3.94 |
| 386.77 | 3.17 | 3.17 |
| 388.31 | 3.11 | 3.11 |
| 368.78 | 3.03 | 3.03 |